𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Synthesis of bicyclic γ-lactones promoted by Mn(OAc)3: Regio- and diastereoselectivities

✍ Scribed by Laurent Lamarque; Alain Méou; Pierre Brun

Book ID
104208584
Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
471 KB
Volume
54
Category
Article
ISSN
0040-4020

No coin nor oath required. For personal study only.

✦ Synopsis

The regio-and diastereoselectivities of Mn(OAc)3-induced addition of monomethyl malonate on some cvcloalkenes and cycloalkaa~enes are studied The latter is great(v improved when starting .from cvcloalkadienes.

📜 SIMILAR VOLUMES

Diastereoselective synthesis of 2,3,4-tr
Diastereoselective synthesis of 2,3,4-trisubstituted γ-lactols and γ-lactones via regio- and stereocontrolled opening of a 1,2-epoxy-4-hydroxyalkyl carbamate with hetero-nucleophiles
✍ Jörg Lüßmann; Dieter Hoppe; Peter G. Jones; Christa Fittschen; George M. Sheldri 📂 Article 📅 1986 🏛 Elsevier Science 🌐 French ⚖ 227 KB

The acid-catalyzed ring opening of the title epoxide 1 takes place at the C-l atom with retention of configuration at C-2 to form 2,3-cis-2-hydroxy-substituted y-lactol deriva= tives 3 In basic media, nucleophiles attack the C-Atom with inversion of configuration yielding 2,3-trans-lactols 5. Oxidat