Synthesis of biaryls using nickel-catalyzed [2+2+2] cocyclization

✍ Scribed by Yoshihiro Sato; Kenji Ohashi; Miwako Mori

• Book ID: 104261728
• Publisher: Elsevier Science
• Year: 1999
• Tongue: French
• Weight: 198 KB
• Volume: 40
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(99)00945-4

✦ Synopsis

Al~ract: Methods of synthesizing biatyls using nickel-catalyzed [2+2+2] cocyclization were developed. Two ways for the synthesis of biaryl using [2+2+2] cocyclization were investigated: one method is that biaryls synthesized from alkyne having a phenyl group and 2 equivalents of acetylene, and the other method is that those were synthesized from ct,c0-diyne having a phenyl group at an ¢x-position and acetylene. The yield is good in each case.