Synthesis of beta-proline like derivatives and their evaluation as sodium channel blockers

✍ Scribed by Marilena Muraglia; Carlo Franchini; Filomena Corbo; Antonio Scilimati; Vincenzo Tortorella; Maria Stefania Sinicropi; Annamaria De Luca; Michela De Bellis; Diana Conte Camerino

• Book ID: 102339298
• Publisher: Journal of Heterocyclic Chemistry
• Year: 2007
• Tongue: English
• Weight: 361 KB
• Volume: 44
• Category: Article
• ISSN: 0022-152X
• DOI: 10.1002/jhet.5570440519

✦ Synopsis

Abstract

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A simple and convenient procedure for the preparation of beta‐proline like derivatives in their racemic and optically active forms has been reported. The compounds have been screened for their potential activity as sodium channel blockers.