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Synthesis of .beta.-lactams by the photochemical extrusion of sulfur dioxide from 1,1-dioxo-4-thiazolidinones

✍ Scribed by Johnson, Mark R.; Fazio, Michael J.; Ward, Donald L.; Sousa, Lynn R.


Book ID
121282705
Publisher
American Chemical Society
Year
1983
Tongue
English
Weight
842 KB
Volume
48
Category
Article
ISSN
0022-3263

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The Enantioselective Synthesis of (+)-Es
✍ Wolfgang Oppolzer; David Anthony Roberts πŸ“‚ Article πŸ“… 1980 πŸ› John Wiley and Sons 🌐 German βš– 176 KB πŸ‘ 1 views

## Abstract The optically pure steroid (+)‐**15** has been synthesized from the easily accessible (+)‐carboxylic acid **11** by a sequence of 7 steps in 50% overall yield. The key steps are the regioselective deprotonation/alkylation **7+13 β†’ 14** and the thermal SO~2~‐extrusion/cycloaddition **14