Synthesis of (−)-bestatin and the Taxotere® side-chain via nitroaldol reaction of (1R)-8-phenylmenthyl glyoxylate
✍ Scribed by Iwona Kudyba; Jerzy Raczko; Janusz Jurczak
- Book ID
- 108284770
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- French
- Weight
- 114 KB
- Volume
- 44
- Category
- Article
- ISSN
- 0040-4039
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📜 SIMILAR VOLUMES
Taking the judicious choice of the Lewis acid employed, the glyoxylate ene reactions are shown to proceed with a high level of either erythro or threo diastereoselection. The utility of the ene methodology is demonstrated through the stereocontrolled synthesis of a 22F&hydroxy-23-carboxylate steroid
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## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v
## Abstract The kinetics of the ene reaction of stearyl acrylate with polybutadiene oils in the temperature range of 180 to 220°C is described. The ene reaction was found to be of pseudo 1st order with respect to stearyl acrylate because of the excess of polybutadiene double bonds. The rate constan