Synthesis of benzylpyridine using copper zeolite and irradiation – a modified method

✍ Scribed by Vikas N Telvekar; Krishnacharya G Akamanchi; Bapu A Chaudhari

• Publisher: Wiley (John Wiley & Sons)
• Year: 1999
• Tongue: English
• Weight: 58 KB
• Volume: 74
• Category: Article
• ISSN: 0268-2575
• DOI: 10.1002/(sici)1097-4660(199908)74:8<812::aid-jctb108>3.0.co;2-r

✦ Synopsis

The rearrangement of benzylpyridinium chloride to 2-and 4-benzylpyridines (Ladenberg rearrangement) using copper(II)-exchanged zeolite-A as a catalyst has been investigated under combined thermal and irradiation conditions. The reaction occurs at a lower temperature ($160 °C) than the usual temperature of 220 °C. A good yield of a mixture of 2-and 4-benzylpyridines was obtained. Moreover, this catalyst could be recycled. The effects of various parameters have been studied and it is concluded that this modi®ed method holds promise for commercialisation.