The title trisaccharide glycosides were needed for studies of the interactions of &tins, receptor sites for bacteriophages with Salmonella lipopolysaccharide corespecificity, and correlation of n.m.r. chemical shifts and structure. The methods used in the syntheses were conventional. Thus, 2,3,4,6-
Synthesis of benzyl 6-O-α-d-mannopyranosyl-1-thio-α-d-mannopyranoside and benzyl 2-O-α-d-mannopyranosyl-1-thio-α- and -β-d-mannopyranoside
✍ Scribed by Philippe L. Durette; Tsung Y. Shen
- Book ID
- 108308823
- Publisher
- Elsevier Science
- Year
- 1979
- Tongue
- English
- Weight
- 496 KB
- Volume
- 69
- Category
- Article
- ISSN
- 0008-6215
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📜 SIMILAR VOLUMES
p-Nitrophenyl 2-O-benzyl-4,5-O-cyclohexylidene-beta-D-mannopyranoside (4) was condensed with tetra-O-benzoyl-alpha-D-mannopyranosyl bromide. The resulting, protected disaccharide was converted into p-nitrophenyl O-(2,3,4-tri-O-benzoyl-alpha-D-mannopyranosyl)-(1----3)-4-O-benzoyl-2-O- benzyl-beta-D-m
During the preparation of simple mannopyranosides using the Koenigs-Knorr type reaction, we observed that a significant amount of disaccharide glycoside was produced when the alcohol was used in amounts less than equivalent of 2,3,4,6-tetra-O-acetyl-c~-D-mannopyranosyl bromide ("acetobromomannose").
Reaction of p-trifluoroacetamidophenyl2,4-di-O-benzyl-a-r>-mannopyranoside with 2-0-acetyl-3,4,6-tri-O-benzyl-cy-D-mannopyranosyl chloride gave a trisaccharide derivative which was 0-deacetylated and then treated with ethyl 2,3,4tri-O-benzyl-6-O-dibenzyloxyphosphoryl-l-thio-a-D-mannopyIanoside. The