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Synthesis of Aziridinomitosenes Through Base-Catalyzed Conjugate Addition.

✍ Scribed by Kazunari Tsuboike; David J. Guerin; Steven M. Mennen; Scott J. Miller


Publisher
John Wiley and Sons
Year
2004
Weight
17 KB
Volume
35
Category
Article
ISSN
0931-7597

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The use of nucleophiles bearing chiral centres, the use of Ξ±,Ξ²the more common sources for the control of asymmetry through Michael addition reactions. unsaturated systems with the chirality at the Ξ³ position and the presence of chiral ligands or other chiral mediators are Scheme 1 Enrique DΔ± Β΄ez-Bar