## Abstract The intramolecular Knoevenagel condensation of __N__‐cyclohexyl 3‐aryl‐2‐(2‐nitrophenyl)acetoxy‐3‐oxopropionamides 4 obtained from 2‐nitrophenylacetic acid (1), arylglyoxals 2 and cyclohexyl isocyanide (3) afforded __N__‐cyclohexyl 3‐aryl‐2,5‐dihydro‐2‐(2‐nitrophenyl)‐5‐oxofuran‐2‐carbo
✦ LIBER ✦
Synthesis of Azine-Type Heterocyclic Compounds and Their Conversion into Functional Molecules
✍ Scribed by Akira Katoh; Ryota Saito
- Publisher
- John Wiley and Sons
- Year
- 2004
- Weight
- 53 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0931-7597
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## Abstract New 4‐aryl‐2,3‐dihydro‐2‐styryl‐1,5‐benzothiazepines **8–13** have been synthesized by an acid catalyzed reaction of 2‐arninothiophenol (**1**) and (__E,E__)‐cinnamylideneacetophenones **2–7.** Ring contraction of 1,5‐benzothiazepines **8–13** provided 2,2‐disubstituted 3‐acetyl‐2,3‐dih