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Synthesis of azabicyclo[4.2.0]octa-1,3,5-trien-8-one analogues of 1H-imidazo[4,5-c]quinoline and evaluation of their antimicrobial and anticancer activities

✍ Scribed by Kayarmar, Reshma; Nagaraja, G. K.; Bhat, Manjunath; Naik, Prashantha; Rajesh, K. P.; Shetty, Suchetha; Arulmoli, T.


Book ID
121595165
Publisher
Springer-Verlag
Year
2013
Tongue
English
Weight
491 KB
Volume
23
Category
Article
ISSN
1054-2523

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## Abstract (__R__)‐5‐(diallylamino)‐5,6‐dihydro‐4__H__‐imidazo[4,5,1‐__ij__]quinolin‐2(1__H__)‐one (__12b__) was prepared in 9% overall yield from 3‐aminoquinoline. Reaction of __12b__ in ethyl acetate with tritium gas in presence of a 5% platinum on carbon catalyst afforded a mixture of (__R__)‐5