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Synthesis of arylsulfonylcarbamic acid derivatives using a new, phosgene-free method

✍ Scribed by Gábor Besenyei; Sándor Németh; László I. Simándi

Book ID
104225916
Publisher
Elsevier Science
Year
1991
Tongue
French
Weight
226 KB
Volume
32
Category
Article
ISSN
0040-4039

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✦ Synopsis

Arylsulfonylcarbamic acid esters, thioesters, and amides, 3, have been prepared via catalytic carbonylation of alkali metal salts of N-chloroarylsulfonamides, 1, and treatment of the reaction mixture with R'XH (X=0, S, NR'). Arylsulfonylcarbamic acid derivatives, ArSO,NHC(O)XRl, 3, (Ar = aryl, x=o,s, Rl=alkyl, aryl; X=NR', Rl=H, alkyl, aryl R2=H, acyl, heteroaryl) such as esters, thioesters and amides (ureas) exhibit useful biological

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