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Synthesis of aryl β-d-mannopyranosides
✍ Scribed by Henry P. Kleine; Ravinder S. Sidhu
- Publisher
- Elsevier Science
- Year
- 1988
- Tongue
- English
- Weight
- 341 KB
- Volume
- 182
- Category
- Article
- ISSN
- 0008-6215
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A non-covalent version of the intramolecular aglycon delivery methodology has been demonstrated for the stereoselective formation of b-D-mannopyranoside in the presence of lanthanide(III) triflate.
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A new stereocontrolled synthesis of b-D-mannopyranosides was defined relying on a high yielding sequence based on the following three key steps: (a) a stereospecific inversion at C-2 of b-D-galactopyranosides by an oxidation-reduction procedure; (b) a regiocontrolled formation of 4-deoxy-b-D-threo-h
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