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Synthesis of Aryl- and Pyridinyl-substituted 2-Amino-6-thioxopyridine-3-carbonitrile Derivatives by TandemMichaelAddition and Cyclization Reactions

✍ Scribed by Krystyna Bogdanowicz-Szwed; Małgorzata Krasodomska

Book ID
106213648
Publisher
Springer Vienna
Year
2006
Tongue
English
Weight
166 KB
Volume
137
Category
Article
ISSN
0026-9247

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The synthesis and transformations of 2-[2-ethoxycarbonyl-2-(2-pyridinyl)ethenyl]amino-3-dimethylaminopropenoates. the synthesis of substituted β-amino-α,β-didehydro-a-amino acid derivatives
✍ Lucija Jukić; Simon Rečnik; Jurij Svete; Branko Stanovnik; Simona GoliČ Grdadoln 📂 Article 📅 2001 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 97 KB

## Abstract Alkyl (Z)‐2‐[(__E__)‐2‐ethoxycarbonyl‐2‐(2‐pyridinyl)ethenyl]amino‐3‐dimethylaminopropenoates **7** and **8** were prepared from ethyl 2‐pyridinylacetate (1) in two steps. Substitution of the dimethylamino group with alkyl‐, aryl‐, or heteroarylamines afforded the corresponding β‐alkyl‐