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Synthesis of antimalarial compounds fosmidomycin and FR900098 through N- or P-alkylation reactions

✍ Scribed by Surisetti Suresh; Dharavath Shyamraj; Mats Larhed


Book ID
118186079
Publisher
Elsevier Science
Year
2013
Tongue
French
Weight
491 KB
Volume
69
Category
Article
ISSN
0040-4020

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## Abstract The intermolecular phospha‐Michael reaction of cyclic and acyclic alkenyl sulfoximines proceeds readily and yields the corresponding phosphanyl sulfoximines in good yield. The asymmetric induction provided by sulfoximine group in C–P bond formation is apparently only low. The configurat