✦ LIBER ✦

Synthesis of Analogues of the Antitumor (1→6)-Branched (1→3)-Glucohexaose

✍ Scribed by You-Lin Zeng; Jian-Jun Zhang; Fan-Zuo Kong

Book ID: 102804054
Publisher: John Wiley and Sons
Year: 2010
Tongue: English
Weight: 667 KB
Volume: 22
Category: Article
ISSN: 0256-7660
DOI: 10.1002/cjoc.20040220514

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

β‐D‐Glcp( 1→3)‐[β‐D‐Glcp‐( 1→6)‐/α‐D‐Manp‐( 1→3)‐β‐D‐Glcp( 1→3)‐[β‐D‐Glcp‐(1→6)‐]D‐Glcp (18) and β‐D‐Glcp( 1→3)‐[β‐D‐Glcp‐( 1→6)‐] α‐D‐Manp‐( 1→3)‐β‐D‐Glcp‐( 1 →3)‐[β‐D‐Glcp‐( 1→6)‐]β‐D‐Glcp‐D‐(1→3)‐Glcp‐1→OMe (29) were synthesized as the analogues of the immunomodulator β‐D‐Glcp‐(1→3)‐[β‐D‐Glcp‐(1→6)‐]α‐D‐Glcp‐(1→3)‐β‐D‐Glcp‐(1→3)‐(β‐D‐Glcp‐(1→6)‐]D‐Glcp through coupling of trisaccharide donors 9 with trisaccharide acceptor 16 and terrasaccharide acceptor 27 followed by deprotection. respectively.

📜 SIMILAR VOLUMES

Synthesis of Analogues of (1 → 6)‐Branch

Synthesis of Analogues of (1 → 6)‐Branched (1 → 3)‐Glucohexaose

✍ Zhao, Wei; Kong, Fanzuo 📂 Article 📅 2004 🏛 Taylor and Francis Group 🌐 English ⚖ 187 KB

Synthesis of 6-Branched Cyclo-(1→3)-gluc

Synthesis of 6-Branched Cyclo-(1→3)-glucohexaose and Glucooctaose.

✍ Zicheng Wu; Fanzuo Kong 📂 Article 📅 2005 🏛 John Wiley and Sons ⚖ 8 KB

Synthesis of mannose-containing analogue

Synthesis of mannose-containing analogues of (1 → 6)-branched (1 → 3)-glucohexaose

✍ Zicheng Wu; Fanzuo Kong 📂 Article 📅 2004 🏛 Elsevier Science 🌐 English ⚖ 319 KB

Highly Efficient Regio- and Stereoselect

Highly Efficient Regio- and Stereoselective Synthesis of β-(1→6)-Branched β-(1→3)-Linked Glucohexaose and Its Analogue

✍ Yue-Tao Yi; Qian-Fei Zhao; Feng-Zhen Qian; Jun Ning 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 87 KB

The β-(1→6)-branched β-(1→3) glucohexaos

The β-(1→6)-branched β-(1→3) glucohexaose and its analogues containing an α-(1→3)-linked bond have similar stimulatory effects on the mouse spleen as Lentinan

✍ Jun Yan; Hongliang Zong; Aiguo Shen; She Chen; Xianglei Yin; Xiaoyun Shen; Weich 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 560 KB

Stereocontrolled synthesis of sulfur-lin

Stereocontrolled synthesis of sulfur-linked analogues of the branched tetrasaccharide repeating-unit of the immunostimulant polysaccharide schizophyllan and of its β-(1 → 3)-branched, β-(1 → 6)-linked isomer

✍ Marie-Odile Contour-Galcera; Yili Ding; Carmen Ortiz-Mellet; Jacques Defaye 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 497 KB

The branched, sulfur-linked tetrasaccharide S-(beta-D-glucopyranosyl)-(1-->3)-S-[(6-S-beta-D-glucopyranosyl)-3,6-dit hio- beta-D-glucopyranosyl]-(1-->3)-S-3-thio-D-glucopyranose (9) has been conveniently prepared by SN2 displacement of the triflate group in 1,2:5,6-di-O-isopropylidene-3-O-trifluorom