An efficient total synthesis of (-)-deoxypodophyllotoxin has been achieved by employing the asymmetric hydrogenation of a-piperonylidenesuccinic acid half ester with a rhodium(I) complex of (S,S)-MOD-DIOP as a
Synthesis of analogues of 4-deoxypodophyllotoxin
✍ Scribed by Andrrew R. Beard; Michael G.B. Drew; John Mann; Lilan T.F. Wong(née Yeung)
- Book ID
- 104203025
- Publisher
- Elsevier Science
- Year
- 1987
- Tongue
- French
- Weight
- 511 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0040-4020
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
AbstractÐ4-Aza-2,3-dehydro-4-deoxypodophyllotoxin analogues 3a±n were synthesized through quinolines 2a±n. Comparison of their cytotoxicity against P-388 leukemia cells revealed that the steric eects of the ring B substituents on the activity are greater than the electronic eects, while the presence
Benzyl 2,3,6-tri-O-benzyl-4-deoxy-4-C-methylenea\_Dranoside (3) was transformed with 3-chloroperoxybenzoic acid into the epoxides 4 and 5. Reductive opening of the epoxide moiety in 4 furnished benzyl 2,3,6-tri-O-benzyl-4-C-methyl-a-o-glucopyranoside (6); subsequent hydrogenolytic Odebenzylation, pe
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v