Synthesis of an isomer of the germacranolide isoaristolactone
β Scribed by Gordon L. Lange; Solomon So; Mark Lautens; Kevin Lohr
- Book ID
- 103397545
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- French
- Weight
- 129 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
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## Tandem conjugate addition by an O-silylcyanohydrin derived carbanion to 5-(1-menthy10xy)-~5~~0~, followed by reaction with an ammatic aldehyde gives two dktereoisomfxic adducts. T&se. afford a single product on treatment with tcrrabutylammonium tluolide. Reduction with concomitant removal of t
## 9H-quino[4,3,2-de][1,10] phenanthrolin-9one) (1) and an isomer (9H-quino[4,3,2-de][1,7]phenanthrolin-9-one) (4) have been synthesized starting from 1,4-dimethoxyacridone (7). The acridone was converted into 1,4-dimethoxy-9-ethynylacridine ( 11) by a triflate coupling. The ethynylacridine was co