Synthesis of an encephalitogenic fragment of the protein of myelin and its 6-glycine analog
โ Scribed by A. A. Gershkovich; V. K. Kibirev; L. M. Fedorchenko; S. B. Serebryanyi
- Book ID
- 112376431
- Publisher
- Springer
- Year
- 1975
- Tongue
- English
- Weight
- 112 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0009-3130
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Immunochemical analysis of polyclonal antisera from Lewis rats immunized with peptide analogs and subpeptides of residues 72-84 of guinea pig myelin basic protein (MBP) indicated that there were four main epitopic specificities involved: one represented by residues 76-80, one by residues 72-74, one
A partially purified myelin basic protein serum factor (MBP-SF), cross-reactive with residues 65-74 (TTHYGSLPQK) of myelin basic protein, has been employed in an immunochemical study to identify the nature of the cross-reacting determinant more precisely. To probe the structural requirements of this