Synthesis of amorphane and cadinane sesquiterpenes from fabiana imbricata
✍ Scribed by Koon-Sin Ngo; Geoffrey D. Brown
- Book ID
- 104209783
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- French
- Weight
- 766 KB
- Volume
- 55
- Category
- Article
- ISSN
- 0040-4020
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✦ Synopsis
The monoterpene (-)-isopulegol(7) has been used as a starting material for the total synthesis in eight/nine steps of hvo sesquiterpenes which were recently isolated from the medicinal plant Fubimu imbrica!u. Use of this approach has shown that a structure proposed as 3,1 I-amorphadiene (3) should be revised to that of 4,l Icadinadiene ( 18) and confmed the structure proposed for the natural product 4-amolphen-1 l-01 (1).
📜 SIMILAR VOLUMES
## Abstract Six new cadinane‐type sesquiterpenes, (1__β__,4__β__,5__α__,10__α__)‐1,4‐epoxymuurolan‐5‐ol (**1**), (4__α__,10__β__)‐4,10‐dihydroxycadin‐1(6)‐en‐5‐one (**2**), (2__β__,3__α__,4__β__,6__β__)‐2,3‐dihydroxycadin‐1(10)‐en‐5‐one (**3**), (2__β__,3__α__)‐__α__‐corocalene‐2,3‐diol (**4**), (7
Oxidation and reduction reactions on two sesquiterpene hydrocarbons, calarene 1 and thujopsene 7, have been investigated in order to produce inexpensive fragrances for perfumery. Oxidation using m-chloroperbenzoic acid gave epoxides, ketones and unsaturated alcohols with a fair selectivity. Reductio