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Synthesis of Aminoalkylpyrazoles and -isoxazoles from Cyclic β-(Trifluoroacetyl) Enamines.

✍ Scribed by V. G. Nenajdenko; S. V. Pronin; E. S. Balenkova

Publisher
John Wiley and Sons
Year
2007
Weight
25 KB
Volume
38
Category
Article
ISSN
0931-7597

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✦ Synopsis

Abstract

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## Abstract Alkylphenyl sulfones **3** are appropriate synthons for the synthesis of 2‐phenylsulfonyl alkylidene pyrro‐lidine or piperidine derivatives **1** in good to moderate yields. The lithium alkyl sulfones **4** are first reacted with the desired protected lactams and then subjected to acidi