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Synthesis of Alkynyl Amino Acids and Peptides and Their Palladium-Catalyzed Coupling to Ferrocene

✍ Scribed by Brosch, Oliver; Weyhermüller, Thomas; Metzler-Nolte, Nils


Book ID
127234114
Publisher
American Chemical Society
Year
1999
Tongue
English
Weight
173 KB
Volume
38
Category
Article
ISSN
0020-1669

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A Two-Step Palladium-Catalyzed Coupling
✍ Oliver Brosch; Thomas Weyhermüller; Nils Metzler-Nolte 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 English ⚖ 416 KB 👁 2 views

This work describes a Pd-catalyzed coupling of ferrocene al-derivative 10) and of course amides. A minor by-product of the coupling reaction, namely the homo-dimer bis(ferrocene kyne derivatives to iodo amino acids. Ferrocene carboxylic acid propargyl amides were easily obtained in high yield. carbo