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Synthesis of alkyl tertiary alkyl ethers using β-zeolite catalysts

✍ Scribed by J.F. Knifton; P.-S.E. Dai


Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
110 KB
Volume
15
Category
Article
ISSN
0144-2449

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Stereospecific synthesis of chiral terti
✍ Yao-Jun Shi; David L. Hughes; James M. McNamara 📂 Article 📅 2003 🏛 Elsevier Science 🌐 French ⚖ 124 KB

Mitsunobu reaction of chiral tertiary alcohol (S)-2 with phenol 3 provides the desired ether (R)-1 in moderate yields at elevated temperatures (80-100°C). The S N 2 displacement pathway is evident by complete inversion of the (S)-alcohol to (R)-ether.