Synthesis of adrenal peptide E and some of its biological activities
β Scribed by Edgar P. Heimer; Theodore J. Lambros; Arthur M. Felix; Gideon Fleminger; Choh Hao Li; Manfred Westphal; Johannes Meienhofer
- Book ID
- 115705540
- Publisher
- Elsevier Science
- Year
- 1983
- Tongue
- English
- Weight
- 490 KB
- Volume
- 225
- Category
- Article
- ISSN
- 0003-9861
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Pseudo-peptide analogues of the C-terminal tetrapeptide of gastrin, in which a peptide bond has been replaced by a CH2-NH bond, i.e. (tert-butyloxycarbonyl)-L-tryptophyl-psi (CH2-NH)-L-leucyl-L-aspartyl-L-phenylalanine amide (8), (tert-butyloxycarbonyl)-L-tryptophyl-L-leucyl-psi (CH2-NH)-L-aspartyl-
## Abstract 1. The extent of racemization and the coupling yield in peptide synthesis were studied under high dilution conditions. The azide method yielded the best results. 2. Five linear pentaβpeptide precursors related to gramicidin S were subjected to cyclization in order to study how the diffe