The 2-(trimethylsilyl)ethyl (TMSEt) beta-glycosides of the Forssman pentasaccharide [alpha-D-GalNAc-(1-->3)-beta-D-GalNAc-(1-->3)-alpha-D-Gal- (1-->4)-beta-D-Gal-(1-->4)-D-Glc] and the terminal tetrasaccharide, as well as the methyl glycosides 1 and 2 of the terminal di- and tri-saccharides, were sy
Synthesis of acylated tri- and tetra-saccharides with one thioureylene group
✍ Scribed by José Fuentes Mota; Tomasa Cuevas; M.Angeles Pradera
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 718 KB
- Volume
- 260
- Category
- Article
- ISSN
- 0008-6215
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✦ Synopsis
a Rings A, B, and C refer to the gluco residue joined to N, the 2,3,4,6-tetra-O-ace@-/3-D-ghKosyl group, and the gluco residue joined to N', respectively. b At 50.3 MHz. ' At 125.7 MHz. d'e'f Assignments may be interchanged.
* For 4 and 5, the protons of rings B and C (see footnote a of Table 1) are named as H" and F-1'. respectively.
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Syntheses of the propyl glycosides (1-3) of beta-D-Galp-(1----4)-beta-D-GlcpNAc, beta-D-Glcp-(1----6)-[beta-D-Galp-(1----4)]-beta-D-GlcpNAc, and beta-D-Galp-(1----4)-beta-D-Glcp-(1----6)-[beta-D-Galp-(1----)]-beta-D- GlcpNAc, respectively, are reported. Reaction of allyl 2-acetamido-3-O-benzyl-2-deo
The methyl glycoside of a tetrasaccharide isolated from heparin, methyl 0-(a-t\_-idopyranosyluronic acidM1 + 4)-O-(2-acetamido-2-deoxy-a-o-glucopyranosyl)-(1 -+ 4)-o-(p-oglucopyranosyluronic acid)-(1 -+ 3)-0-P-o-gafactopyranoside disodium salt and a trisaccharide derivative thereof, methyl 0-(a-L-id