Synthesis of activated cyclophosphamide derivatives bearing functional groups

✍ Scribed by Takashi Hirano; Wolfgang Klesse; Joerg H. Heusinger; Gabriele Lambert; Helmut Ringsdorf

• Book ID: 104244693
• Publisher: Elsevier Science
• Year: 1979
• Tongue: French
• Weight: 255 KB
• Volume: 20
• Category: Article
• ISSN: 0040-4039
• DOI: 10.1016/s0040-4039(01)93578-6

✦ Synopsis

This paper describes the synthesis of stabilized 4-hydroxy-cyclophosphamide derivatives with functional groups for the further modification of these active anti-tumor agents, especially for their fixation to polymeric carriers.