Synthesis of Acerogenin C and (+)-Acerogenin A, Two Macrocyclic Diarylheptanoid Constituents of Acer nikoense

✍ Scribed by György Miklós Keserü; Mihály Nógrádi; Áron Szöllösy

• Publisher: John Wiley and Sons
• Year: 1998
• Tongue: English
• Weight: 374 KB
• Volume: 1998
• Category: Article
• ISSN: 1434-193X
• DOI: 10.1002/(sici)1099-0690(199803)1998:3<521::aid-ejoc521>3.0.co;2-i

✦ Synopsis

The macrocyclic ketone acerogenin C (3) and the correspon-steps were the selective reduction of the double bond of an α,β-unsaturated ketone (10) and macrocyclization of an iodo-ding alcohol (+)-accerogenin A (1), diarylheptanoid constituents of the maple Acer nikoense were synthesized. The key phenol (13) by a modified Ullmann diarylether synthesis.