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Synthesis of a β-glycoside functionalized GΛC motif for self-assembly into rosette nanotubes with predefined length

✍ Scribed by Rachel L. Beingessner; Julian A. Diaz; Usha D. Hemraz; Hicham Fenniri


Publisher
Elsevier Science
Year
2011
Tongue
French
Weight
548 KB
Volume
52
Category
Article
ISSN
0040-4039

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✦ Synopsis


Progress toward the synthesis of guanine-cytosine (GKC) oligonucleotides for the spontaneous selfassembly of rosette nanotubes (RNTs) with predefined length is described. Highlighted is the synthesis of the b-glycoside functionalized GKC base along with a new nitrogen protecting group strategy that is compatible with Boc and Bn groups.