Synthesis of a potential steroid intermediate by anionic oxy-cope rearrangement
โ Scribed by G. Sathyamoorthi; K. Thangaraj; P.C. Srinivasan; S. Swaminathan
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- French
- Weight
- 122 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
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Synthesis of 2-acetoxy[5]helicene has been achieved by sequential double aromatic oxy-Cope rearrangement strategy. Combination of 1-methoxybicyclo[2.2.2]oct-5-en-2-one and p-bromophenylmagnesium bromide gave 3-bromophenanthrene through several steps including an aromatic oxy-Cope rearrangement as a