Synthesis of a Phosphatidylinositol 3,4,5-Trisphosphate
โ Scribed by Yutaka Watanabe; Hajimu Hirofuji; Shoichiro Ozaki
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- French
- Weight
- 156 KB
- Volume
- 35
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
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Phosphatidylinositol 3,4,5-trisphosphate (PIP(3)), a primary output signal of phosphoinositide (PI) 3-kinase, plays a crucial role in diverse cellular processes. Evidence indicates that PIP(3) exerts downstream signaling, in part, by recruiting effector proteins to plasma membranes. Consequently, id
Phosphatidylinositol-3,4,5-trisphosphate (PI(3,4,5)P 3 (1), Scheme 1) [1] is a second messenger that mediates many intracellular processes including cell proliferation, migration, and survival. The lipid is predominantly located in the