Synthesis of a Novel Enantiopure Spiro-B
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Lutz F. Tietze; J. Matthias Wiegand; Carsten A. Vock
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Article
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2004
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John Wiley and Sons
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English
⚖ 150 KB
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## Abstract The novel tetracyclic spiro compound **13** was synthesized by the use of two subsequent Pd‐catalyzed reactions. Firstly, the __ortho__‐bromobenzyl chloride **1** was coupled with the enantiopure boronic ester **8**, obtained from the Hajos−Wiechert ketone in a chemoselective Suzuki‐typ