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Synthesis of a novel class of fatty acids-derived isoquinolines

✍ Scribed by Iwona Matuszewska; Andrzej Leniewski; Piotr Roszkowski; Zbigniew Czarnocki


Book ID
108089325
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
280 KB
Volume
135
Category
Article
ISSN
0009-3084

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## Abstract 10‐Fluorodecan‐9‐olide (1a), a monofluorinated analogue of (±)‐phoracantholide, is synthesised in 20% overall yield by a five‐step sequence starting with 9‐decenoic acid (3a). 10‐Undecenoic acid (3b) is transformed in 28% overall yield into the next higher homologue, 11‐fluoroundecan‐10