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Synthesis of a Novel Bridged Nucleoside Bearing a Fused-Azetidine Ring, 3′-Amino-3′,4′-BNA Monomer.

✍ Scribed by Satoshi Obika; Jyun-ichi Andoh; Mayumi Onoda; Osamu Nakagawa; Akiko Hiroto; Tomomi Sugimoto; Takeshi Imanishi


Publisher
John Wiley and Sons
Year
2003
Weight
59 KB
Volume
34
Category
Article
ISSN
0931-7597

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✍ Huan-Ming Chen; Ramachandra S. Hosmane; Donna M. Baldisseri 📂 Article 📅 2000 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 217 KB

## Abstract The synthesis of a novel ring‐expanded nucleoside analogue, (Z)‐1‐((2‐Guanidinocarbamoyl‐cyclopropylidene)methyl)‐4,5,7,8‐tetrahydro‐6__H__‐6‐iminoimidazo[4,5‐__e__][1,3]diazepine‐4,8‐dione (**1**) has been reported. It was prepared starting from methyl imidazole‐4,5‐dicarboxylate by se