Synthesis of a Norsesquiterpene Spirolactone/Steroidal Hybrid by Using an Environmentally Friendly Domino Reaction as a Key Step
✍ Scribed by Angéline Chanu; Imad Safir; Ramkrishna Basak; Angèle Chiaroni; Siméon Arseniyadis
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 203 KB
- Volume
- 2007
- Category
- Article
- ISSN
- 1434-193X
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
One-Pot Synthesis of Chiral Aziridines dure is simple, this method offers an efficient route for the preparation of chiral aziridine derivatives.
## Abstract The reaction of (I) with aldehydes (II) leads to a dia‐ and enantioselective formation of adducts (III).
Pyrimethamine 1 is a folic acid reductase inhibitor. In this molecule the ring nitrogen is flanked by two functional groups, which is essential to the biological activity of pyrimethamine. Also, a plethora of aminopterin 2 and 2,4-diamino-6-substituted quinazoline antifolates 3 exhibit strong antima