Synthesis of a New Turn Mimic Bearing a β-Lactam Moiety
✍ Scribed by Thomas C. Maier; Wolfgang U. Frey; Joachim Podlech
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 97 KB
- Volume
- 2002
- Category
- Article
- ISSN
- 1434-193X
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## Abstract Es wird eine neue Synthese von β‐Lactamen durch Umsatz von 4‐Alkylazlactonen mit acyclischen Iminen beschrieben. Mit einem cyclischen Imin wird dagegen ein Imidazolin‐Derivat erhalten.
## Abstract Reported here is an easy and short synthesis of 6‐acetamido‐5‐oxo‐1,2,3,5,6,7‐hexahydro‐3‐indolizine‐carboxylic acid, originating from β‐enaminoesters derived from pyroglutamic acid. This key compound has been used as a scaffold in the synthesis of dipeptido mimetics.
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