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Synthesis of a new substrate analog of firefly luciferin. Active-site probe

✍ Scribed by Bowie, Lemuel J.; Horak, Vaclav; DeLuca, Marlene


Book ID
127377491
Publisher
American Chemical Society
Year
1973
Tongue
English
Weight
882 KB
Volume
12
Category
Article
ISSN
0006-2960

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Cypridina bioluminescence VI a new route
✍ S. Inoue; S. Sugiura; H. Kakoi; T. Goto πŸ“‚ Article πŸ“… 1969 πŸ› Elsevier Science 🌐 French βš– 106 KB

A total synthesis of Cypridina luciferin (I), a bioluminescent substance obtained from Cypridina hilgendorfii (l), was achieved in 1966 (2) by reductive condensation of an appropriate 2-aminopyrazine derivative and a-keto acid, but the yield was too low to use th!s route for preparative purposes. Tw