Synthesis of a new enantiopure chiral aza crown ether and its application in enantiomeric separation
β Scribed by Cheng-Yun Wang; Da-Hui Wang; Tao-Hua Leng; Qing-Sen Yu
- Publisher
- Journal of Heterocyclic Chemistry
- Year
- 2005
- Tongue
- English
- Weight
- 68 KB
- Volume
- 42
- Category
- Article
- ISSN
- 0022-152X
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β¦ Synopsis
A new enantiopure chiral aza crown ether (S,S)-1,7-bis(4-phenyl-5-hydroxy-2-oxo-3-zapentyl)-1,7diaza-12-crown-4 ligand (1) has been synthesized and used as a chiral selector in the enantiomeric separation of D/L-carnitine by capillary electrophoresis.
π SIMILAR VOLUMES
A new enantiomerically pure P-chiral phosphine, (S)-cyclohexylmethyl- (1-naphthyl)phosphine (1) was prepared by phosphine-borane methodology and used in a mechanistic study of the Mitsunobu reaction. Enantiomerically enriched (S)-cyclo- hexylmethyl(1-naphtyl)phosphine oxide (8) is obtained if the re