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Synthesis of a New Class of Druglike Angiotensin II C-Terminal Mimics with Affinity for the AT 2 Receptor

✍ Scribed by Georgsson, Jennie; Sköld, Christian; Botros, Milad; Lindeberg, Gunnar; Nyberg, Fred; Karlén, Anders; Hallberg, Anders; Larhed, Mats

Book ID
126485246
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
214 KB
Volume
50
Category
Article
ISSN
0022-2623

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Interaction of angiotensin II with the C
Interaction of angiotensin II with the C-terminal 300–320 fragment of the rat angiotensin II receptor AT1a monitored by NMR
✍ Nicola D'Amelio; Elena Gaggelli; Nicola Gaggelli; Luisa Lozzi; Paolo Neri; Danie 📂 Article 📅 2003 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 319 KB

## Abstract Interaction between angiotensin II (Ang II) and the fragment peptide 300–320 (__fCT__^__300–320__^) of the rat angiotensin II receptor AT~1a~ was demonstrated by relaxation measurements, NOE effects, chemical shift variations, and CD measurements. The correlation times modulating dipola