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Synthesis of a new benzo[a]phenothiazine amino alcohol as a proposed antimalarial

✍ Scribed by Prakash C. Taunk

Book ID
112127974
Publisher
Journal of Heterocyclic Chemistry
Year
1985
Tongue
English
Weight
117 KB
Volume
22
Category
Article
ISSN
0022-152X

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The usual pathwsys' for preparing ~-amino alcohols for use in the Tiffeneau-Demjanov reaction involve either preparation of cyanohydrins or t3-nitroalcohols fYan ketones, followed by reduction. Difficulty is encountered with some conjugated and sterically hindered ketones with the initisl addition r