SYNTHESIS OF A NEW AZATETRACYCLODECANE RING SYSTEM via INTRAMOLECULAR ADDITION OF AZIDE ON DOUBLE BOND
✍ Scribed by Berényi, S.; Gulyás, Gy.; Batta, Gy.; Makleit, S.
- Book ID
- 126035066
- Publisher
- Taylor and Francis Group
- Year
- 1991
- Tongue
- English
- Weight
- 207 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0030-4948
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In the course of our search for biologically active agents, we discovered a novel heterocyclizatinn reaction. We wish to report details of the reaction and then comment on possible mechanisms implicated in the cyclization. When an aqueous solution of 7-methyl-7-azabicycloL4.l.O]heptane (1) and 2 eq
Tricyclic ketones 3 B and 2-s having angularly fused 5-6-5 or 5-7-5 ring system have been efficiently prepared by irradiation of bicyclic enones \_& and 1. Angularly fused tricyclic ring systems have been attracted increasing interest because many natural products which possess this new type of carb