of either N-benzoylalanine or N-acetylphenylgllcine. The preparative application of this new pyrrole synthesis is simplified by the fact that alkyloxazolones, which are unstable and difficult lo purify [I], can be used in sifu. Thus, (5) is obtained by the reaction of phenylglycine or N-acetylphenyl
Synthesis of a mesoionic imidazole system and studies of its participation in 1:3 dipolar cycloaddition reactions
โ Scribed by Gurbakhsh Singh; P.S. Pande
- Book ID
- 104244282
- Publisher
- Elsevier Science
- Year
- 1974
- Tongue
- French
- Weight
- 116 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0040-4039
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โฆ Synopsis
The monocyclic mesoionic imidazole system has previously been described only as its 5-acyl derivatives. ',2 These were found to be unreactive towards dipolarophiles due to the internal stabilization of the system through resonance participation with the acyl carbonyl function.3 We now wish to report the
๐ SIMILAR VOLUMES
A simple and efficient method for the synthesis of novel spiropyrrolidines has been accomplished by regioselective 1,3-dipolar cycloaddition reactions of an azomethine ylide generated by thermalring opening of cis-1-cyclohexyl-2-phenyl-3-benzoyl aziridine with various (E)-3-arylidene-4-chromanones.
Rate constants for the cycloadditlons of 3,4.5.6-tetrahydropyridine l-oxide Q), and 3-oxo-3,4,5,6-tetrahydropyridlne l-oxide (2)Ito several mom-and disubstituted alkeoes have been determined at 36'C by H NtdR Spectroscopy. Small soLvent effect oa the rate constant indicate the concerted nature of t