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Synthesis of a library of glycosylated flavonols

โœ Scribed by Zhitao Li; George Ngojeh; Paul DeWitt; Zhi Zheng; Min Chen; Brendan Lainhart; Vincent Li; Peter Felpo

Book ID
104095922
Publisher
Elsevier Science
Year
2008
Tongue
French
Weight
149 KB
Volume
49
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

Flavonols are an important class of natural products isolated from plants. Some glycosylated flavonols showed very interesting biological activities. A library of flavonols has been made through Algar-Flynn-Oyamada reaction from 2'-hydroxyacetophenones and benzaldehydes. Glycosylation of these flavonols with various glycosyl donors affords a library of glycosylated flavonols. These compounds are potentially useful pharmacologically active compounds and will be studied for biological activities.

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A new synthesis of flavonols
A new synthesis of flavonols
โœ H. Fletcher; E.M. Philbin; P.D. Thornton; T.S. Wheeler ๐Ÿ“‚ Article ๐Ÿ“… 1959 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 77 KB

FUVONOIS (III) are ueually prepared by the Alga+Flynn-Oyamada reaction 1,2 or by the Allan-Robinson uiethod.3 The new eyntheeie here deeoribed involvee the oxidation of g-hydroxydibeneoylmethanee with performic aoia in ohlorofora, Karrer et al, 4 obeerved the formation of diben~oylcarbinols .=R=RkH;