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Synthesis of a hybrid analog of the acetylcholinesterase inhibitors huperzine A and huperzine B

✍ Scribed by V Rajendran; Suo-Bao Rong; Ashima Saxena; Bhupendra P Doctor; Alan P Kozikowski

Book ID
104231069
Publisher
Elsevier Science
Year
2001
Tongue
French
Weight
84 KB
Volume
42
Category
Article
ISSN
0040-4039

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πŸ“œ SIMILAR VOLUMES

ChemInform Abstract: Synthesis of a Hybr
ChemInform Abstract: Synthesis of a Hybrid Analogue (I) of the Acetylcholinesterase Inhibitors Huperzine A and Huperzine B.
✍ V. Rajendran; Suo-Bao Rong; Ashima Saxena; Bhupendra P. Doctor; Alan P. Kozikows πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons βš– 26 KB πŸ‘ 2 views

## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a β€œFull Text” option. The original article is trackable v

Synthesis of the Thiazolone Analogue of
Synthesis of the Thiazolone Analogue of the Acetylcholinesterase Inhibitor, Huperzine A
✍ Alan P. Kozikowski; Werner TΓΌckmantel; Ashima Saxena; Bhupendra P. Doctor πŸ“‚ Article πŸ“… 1994 πŸ› John Wiley and Sons 🌐 German βš– 792 KB

## Abstract The preparation of an analogue 3a of the acetylcholinesterase inhibitor, huperzine A (1), is described in which the pyridinone moiety of the natural product is replaced with a thiazolone moiety. The synthesis started from cyclohexane‐1,4‐dione monoethylene ketal (7) by first annulating