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Synthesis of a hindered C2-symmetric hydrazine and diamine by a crisscross cycloaddition of citronellal azine

โœ Scribed by Snider, Barry B; Grabowski, James F; Alder, Roger W; Foxman, Bruce M; Yang, Lin


Book ID
111945638
Publisher
NRC Research Press
Year
2006
Tongue
French
Weight
481 KB
Volume
84
Category
Article
ISSN
0008-4042

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Enantiospecific synthesis of a rigid, C2
โœ E.J Corey; Mitsuaki Ohtani ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 218 KB

A broadly applicable method has been demonstrated for the efficient synthesis of chiral bicyclic guanidines such as 1 from chiral a-amino acids. Compounds containing the guanidine unit are of considerable biological interest because of the hydrogen-bond mediated interaction of guanidinium ions with