𝔖 Bobbio Scriptorium
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Synthesis of a highly tritiated photoaffinity labelled pheromone analog for the moth antheraea polyphemus

✍ Scribed by Glenn D. Prestwich; Frederick A. Golec Jr.; Niels H. Andersen


Publisher
John Wiley and Sons
Year
1984
Tongue
French
Weight
375 KB
Volume
21
Category
Article
ISSN
0022-2135

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✦ Synopsis


Abstract

The synthesis of the tritiated sex pheromone of the saturniid moth Antheraea polyphemus was accomplished by stereospecific T~2~ reduction of (E)‐hexadec‐6‐en‐11‐yn‐1‐yl acetate. The [11, 12‐^3^H~2~]‐(E, Z)‐6, 11‐hexadecadieny 1 acetate was then converted to the corresponding diazoacetate, a behaviorally active photoaffinity label for the A. polyphemus pheromone binding and receptor proteins. Synthesis of the enyne precursors is also described.