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Synthesis of a Glycosylphosphatidylinositol Anchor Bearing Unsaturated Lipid Chains

✍ Scribed by Swarts, Benjamin M.; Guo, Zhongwu


Book ID
120324585
Publisher
American Chemical Society
Year
2010
Tongue
English
Weight
509 KB
Volume
132
Category
Article
ISSN
0002-7863

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Total Synthesis of a Glycosylphosphatidy
✍ Dr. Srinivas Burgula; Dr. Benjamin M. Swarts; Prof.β€…Dr. Zhongwu Guo πŸ“‚ Article πŸ“… 2011 πŸ› John Wiley and Sons 🌐 English βš– 352 KB πŸ‘ 1 views

## Abstract The first total synthesis of a glycosylphosphatidylinositol (GPI) anchor bearing a polyunsaturated arachidonoyl fatty acid is reported. This lipid is found in mammalian GPIs that do not undergo lipid remodeling, a process that has important implications in the localization and function