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Synthesis of a Focused Chemical Library Based on Derivatives of Embelin, a Natural Product with Proapoptotic and Anticancer Properties

✍ Scribed by Guillaume Viault; Danielle Grée; Saibal Das; Jhillu Singh Yadav; René Grée


Book ID
102830045
Publisher
John Wiley and Sons
Year
2011
Tongue
English
Weight
688 KB
Volume
2011
Category
Article
ISSN
1434-193X

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✍ Rohan A. Davis; Gregory K. Pierens; Peter G. Parsons 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 111 KB

## Abstract Parallel solution‐phase chemistry has yielded a series of secondary amide analogues of the fungal natural product 3‐chloro‐4‐hydroxyphenylacetamide. 3‐Chloro‐4‐hydroxyphenylacetic acid was coupled to a variety of primary amines using 1‐ethyl‐3‐(3′‐dimethylamino‐ propyl)‐carbodiimide hyd