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Synthesis of a Fluorinated Ganciclovir Analog

✍ Scribed by Sznaidman, Marcos L.; Beauchamp, Lilia M.


Book ID
121204761
Publisher
Taylor and Francis Group
Year
1996
Tongue
English
Weight
315 KB
Volume
15
Category
Article
ISSN
0732-8311

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Synthesis and conformational analysis of
✍ Stefan E. Boiadjiev; David A. Lightner πŸ“‚ Article πŸ“… 1999 πŸ› Journal of Heterocyclic Chemistry 🌐 English βš– 629 KB

## Abstract An optically active analog 1 of etiobilirubin‐IVΞ³ with a single fluorine on each of the C(8) and C(12) alkyl groups has been synthesized in order to examine its potential for hydrogen bonding with fluorine. Circular dichroism spectroscopy reveals an unusually strong influence of 2,2,2‐t