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Synthesis of a Carbon-Linked Mimic of the Disaccharide Component of the Tumor-Related SialylTn Antigen

✍ Scribed by Zouleika Abdallah; Gilles Doisneau; Jean-Marie Beau

Book ID
101527761
Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
133 KB
Volume
115
Category
Article
ISSN
0044-8249

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πŸ“œ SIMILAR VOLUMES

Synthesis of a Carbon-Linked Mimic of th
Synthesis of a Carbon-Linked Mimic of the Disaccharide Component of the Tumor-Related SialylTn Antigen
✍ Zouleika Abdallah; Gilles Doisneau; Jean-Marie Beau πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 133 KB

Among the large number of known tumor-associated carbohydrate motifs, Tn (GalNAca1!O-Ser/Thr) and sialylTn (Neu5Aca2!6GalNAca1!O-Ser/Thr) are the most specific to human epithelial tumor cells (breast, colon, ovarian, lung, and pancreatic cancers). [1] The sialylTn antigen, which is expressed on memb

Synthesis of a disaccharide component of
Synthesis of a disaccharide component of the capsular polysaccharide antigen of Streptococcus pneumoniae type 1
✍ Hans LΓΆnn; JΓΆrgen LΓΆnngren πŸ“‚ Article πŸ“… 1984 πŸ› Elsevier Science 🌐 English βš– 415 KB

Methyl 2-acetamido-4-amino-2,4,6-trideoxy-3-0-(~-D-galactopyranosyl-uronit acid)-cY-D-galactopyranoside has been synthesised. The parent disaccharide is a structural element of the capsular polysaccharide antigen of Streptococcus pneumoniae type 1.