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Synthesis of a carbon-11 labelled agonist of the α7 nicotinic acetylcholine receptors

✍ Scribed by F. Dollé; F. Hinnen; H. Valette; S. Demphel; C. Coulon; M. Ottaviani; M. Bottlaender; C. Crouzel

Book ID
112132533
Publisher
John Wiley and Sons
Year
2001
Tongue
French
Weight
118 KB
Volume
44
Category
Article
ISSN
0022-2135

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Synthesis and preliminary evaluation of
Synthesis and preliminary evaluation of a carbon-11-labelled agonist of the α7 nicotinic acetylcholine receptor
✍ Frédéric Dolle; Héric Valette; Françoise Hinnen; Françoise Vaufrey; Stéphane Dem 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 183 KB

## Abstract The lead compound of a new series of azabicyclic carbamates described by Astra Laboratories as ligands for the __α__7 nicotinic acetylcholine receptor subtype, namely __N__‐(4‐bromophenyl)carbamic acid quinuclidin‐3‐yl ester, has been labelled with carbon‐11 using no‐carrier‐added [^11^