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Synthesis of a biotin conjugate of the PCP analogue “metaphit” for potential use in NMDA/PCP receptor isolation

✍ Scribed by Alan P. Kozikowski; Werner Tückmantel; Karl Krueger

Publisher
Elsevier Science
Year
1989
Tongue
French
Weight
281 KB
Volume
30
Category
Article
ISSN
0040-4039

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✍ Konstantinos Papadopoulos; Douglas W Young 📂 Article 📅 2002 🏛 Elsevier Science 🌐 French ⚖ 131 KB

The activated b-lactam aldehydes 31 and 55 were synthesised and found to be excellent substrates for our 'ring switching' strategy for preparation of libraries of homochiral compounds with potential for activity at specific glutamate receptor sub-types. The product heteroaromatic glycine derivatives